Table of Contents

Syncope: What Are The Causes, Symptoms, and Treatment

Syncope, commonly referred to as fainting, is the sudden and temporary loss of consciousness due to reduced blood flow to the brain. This condition occurs when there is not enough oxygenated blood circulating in the brain, leading to a temporary drop in blood pressure and heart rate. Although syncope itself is often harmless, it can sometimes signal serious underlying medical conditions, particularly related to heart disease. Understanding the different types of syncope and their triggers is crucial in diagnosing and managing the condition.

One common form of fainting is neurally mediated syncope (NMS), which is often encountered in emergency situations. NMS is characterized by its benign nature and is prevalent among children and young adults.

In this article, we will explore the causes, symptoms, risk factors, diagnostic methods, and treatments for syncope, including terms such as vasovagal syncope, cardiac syncope, postural orthostatic tachycardia syndrome, and more.

What Is Syncope?

Syncope is defined as a brief loss of consciousness caused by a temporary reduction in blood flow to the brain. This reduction in blood flow can be due to various reasons, including problems with the heart’s electrical system, abnormal heart rhythms, or low blood pressure. Abnormal heart rhythm, in particular, is significant in the functioning of the heart and is often monitored diagnostically to prevent serious cardiovascular conditions. While syncope can happen to anyone, young adults and older individuals are particularly at risk. The most common types of syncope include vasovagal syncope, cardiac syncope, and neurologic syncope.

Syncope can occur without warning, and in some cases, it may result in injury, such as a head injury from a fall. The condition can be distressing, and recurrent syncope may indicate an underlying medical issue that requires thorough evaluation.

Types of Syncope: Vasovagal Syncope

Vasovagal Syncope
  1. Vasovagal Syncope: Also called neurocardiogenic syncope, this is the most common type of fainting, often triggered by emotional distress, pain, or prolonged standing. It occurs when the autonomic nervous system overreacts to certain stimuli, causing a temporary drop in blood pressure and heart rate, leading to fainting. Vasovagal syncope can also result from triggers like the sight of blood or extreme fear.
  2. Cardiac Syncope: This type is caused by abnormal heart rhythms, structural heart disease, or blood flow obstruction. Conditions like ventricular tachycardia, aortic stenosis, mitral stenosis, and atrial fibrillation can cause cardiac syncope. Since cardiac syncope can lead to serious complications such as sudden cardiac death, it requires prompt medical attention.
  3. Orthostatic Hypotension: Also known as postural syncope, this occurs when there is a significant drop in blood pressure upon standing up, leading to fainting. It is often seen in individuals with low blood volume, dehydration, or those on certain medications that affect blood flow. This type of syncope can also be related to postural orthostatic tachycardia syndrome (POTS), which causes an abnormal increase in heart rate upon standing.
  4. Situational Syncope: This is a form of reflex syncope, where specific physical activities like coughing, swallowing, urinating, or defecating trigger a fainting episode. These activities may overstimulate the autonomic nervous system, resulting in a temporary reduction of blood flow to the brain.
  5. Carotid Sinus Syncope: This type of syncope is related to carotid sinus hypersensitivity, where pressure on the carotid artery (such as during neck movements or tight collars) can cause a sudden drop in blood pressure, leading to fainting. It is more common in older adults.
  6. Neurologic Syncope: This type is caused by neurological conditions such as Parkinson’s disease, seizures, or transient ischemic attacks (mini-strokes). It can be related to abnormalities in the nervous system that disrupt blood flow to the brain.
  7. Neurally Mediated Syncope: Also known as NMS, this common form of fainting is often encountered in emergency situations. It is characterized by a benign nature and is prevalent among children and young adults. Triggers include emotional stress, pain, or prolonged standing, leading to physiological responses such as a temporary drop in blood pressure and heart rate. Understanding its implications and management is crucial, as it encompasses various subcategories of syncope.

Causes and Risk Factors of Syncope: Abnormal Heart Rhythm

Several factors can lead to syncope, and they vary depending on the type of syncope. Some common causes include:

  • Vasovagal Syncope: Triggered by emotional or physical stress, such as fear, pain, or prolonged standing.
  • Cardiac Syncope: Caused by abnormal heart rhythms (e.g., sinus bradycardia, ventricular tachycardia), structural heart diseases like aortic stenosis and mitral stenosis, or blood flow obstruction due to pulmonary embolism or blood clots. Abnormal heart rhythm can lead to inefficient blood circulation and potential fainting episodes due to serious cardiovascular conditions.
  • Orthostatic Hypotension: Caused by a sudden drop in blood pressure due to dehydration, medication, or postural hypotension.
  • Neurologic Syncope: Related to conditions like Parkinson’s disease, seizures, or strokes.
  • Carotid Sinus Syncope: Triggered by pressure on the carotid artery, which can lead to a temporary drop in blood pressure.
  • Low Blood Sugar: Low glucose levels can reduce blood flow to the brain, causing fainting.
  • Blood Vessel Conditions: Problems with blood vessels, such as narrowing or blockage, can also contribute to syncope.

Risk factors for syncope include:

  • Heart disease or cardiac disease
  • Abnormal heart rhythms
  • Higher risk of sudden death due to conditions like ventricular tachycardia or aortic stenosis
  • History of recurrent syncope
  • Blood vessel conditions
  • Increased risk for those with neurological conditions
  • Individuals with low blood pressure or blood volume problems

Symptoms of Syncope: Orthostatic Hypotension

Before fainting, people may experience warning signs, including:

  • Dizziness or lightheadedness
  • Tunnel vision
  • Chest pain
  • Palpitations (irregular heartbeats)
  • Sweating
  • Nausea
  • Blurred vision

When syncope occurs, the person will experience a sudden loss of consciousness and fall. Recovery typically happens within a few minutes once blood flow to the brain is restored.

Diagnostic Evaluation for Syncope

To properly diagnose syncope and determine its cause, healthcare providers will perform an initial evaluation and may recommend various diagnostic tests:

  1. Medical History and Physical Examination: The doctor will review the patient’s medical history, including any history of heart conditions, fainting episodes, and medications. A thorough physical examination will also be performed, focusing on heart function, blood pressure, and neurological signs.
  2. Electrocardiogram (ECG): An ECG records the heart’s electrical activity to detect abnormal heart rhythms or heart disease. Detecting an abnormal heart rhythm is crucial as it can indicate serious cardiovascular conditions, leading to inefficient blood circulation and potential fainting episodes.
  3. Tilt Table Test: This test is used to diagnose orthostatic syncope and vasovagal syncope. The patient is strapped to a table that is tilted at different angles to observe changes in heart rate and blood pressure.
  4. Carotid Sinus Massage: To test for carotid sinus syncope, the doctor applies pressure to the carotid artery to see if it triggers a fainting episode.
  5. Blood Tests: Blood tests can identify underlying issues such as low blood sugar, electrolyte imbalances, or blood clot disorders.
  6. Imaging Tests: In cases of suspected structural heart disease or blood flow obstruction, imaging tests such as echocardiograms or MRIs may be recommended.

Treatment of Syncope

Treatment for syncope depends on the underlying cause:

  • Lifestyle Modifications: For individuals with vasovagal syncope, avoiding known triggers such as standing for long periods, staying hydrated, and using compression stockings can help prevent fainting episodes.
  • Medications: Medications to control abnormal heart rhythms, increase blood pressure, or manage conditions like postural orthostatic tachycardia syndrome may be prescribed.
  • Pacemakers and ICDs: For those with cardiac syncope due to heart rhythm issues, a pacemaker or implantable cardioverter-defibrillator (ICD) may be needed to regulate the heart’s electrical system.
  • Surgery: For patients with blood flow obstructions like aortic stenosis or mitral stenosis, surgical intervention may be necessary to improve blood flow.

Complications of Syncope

Syncope can lead to various complications, some of which can be life-threatening. When a person faints, they are at risk of falling and sustaining injuries such as fractures or head trauma. This is particularly concerning for older adults, who may have a higher risk of serious injury from falls. Additionally, if syncope is caused by a cardiac issue, such as ventricular tachycardia or structural heart disease, there is a heightened risk of sudden cardiac death.

Recurrent syncope can also significantly impact a person’s quality of life. Frequent fainting episodes can lead to anxiety and fear of future episodes, which may limit daily activities and social interactions. In severe cases, individuals may need to make substantial lifestyle changes to avoid triggers, which can be disruptive and challenging.

Moreover, untreated or poorly managed syncope can lead to complications related to the underlying cause. For instance, if syncope is due to a condition like postural orthostatic tachycardia syndrome (POTS) or orthostatic hypotension, ongoing issues with blood pressure regulation can cause chronic symptoms and further health problems. Therefore, it is crucial to identify and treat the root cause of syncope to prevent these potential complications.

Managing Syncope

Managing syncope

Managing syncope requires a comprehensive approach that includes lifestyle modifications, medical treatment, and in some cases, surgical interventions. The first step in managing syncope is to identify and address the underlying cause. For those with vasovagal syncope, lifestyle changes such as avoiding known triggers, staying hydrated, and using compression stockings can be effective in preventing fainting episodes.

Medical treatment may be necessary for individuals with cardiac syncope or other serious underlying conditions. Medications can help control abnormal heart rhythms, increase blood pressure, or manage conditions like postural orthostatic tachycardia syndrome. In some cases, a pacemaker or implantable cardioverter-defibrillator (ICD) may be required to regulate the heart’s electrical system and prevent life-threatening arrhythmias.

Surgical interventions may be needed for patients with structural heart disease or blood flow obstructions. Procedures such as valve repair or replacement can improve blood flow and reduce the risk of syncope. Additionally, for those with carotid sinus syncope, surgical options may be considered if conservative treatments are ineffective.

Ongoing monitoring and follow-up care are essential for managing syncope. Regular check-ups with a healthcare provider can help ensure that the treatment plan is effective and make adjustments as needed. By taking a proactive approach to managing syncope, individuals can reduce the frequency of fainting episodes, prevent complications, and improve their overall quality of life.

Preventing Syncope

Preventing syncope involves addressing the root cause and taking precautions to avoid triggers. Some preventive strategies include:

  • Staying well-hydrated to avoid postural hypotension
  • Recognizing early signs of fainting, such as tunnel vision or dizziness, and lying down to restore blood flow
  • Treating underlying conditions like heart disease or neurological conditions
  • Avoiding standing for prolonged periods or exposure to extreme heat

When to Seek Medical Help

If syncope occurs frequently or is accompanied by symptoms such as chest pain, shortness of breath, or palpitations, it is important to seek medical attention. Emergency department visits are recommended if fainting is related to serious causes like cardiac disease or blood flow obstruction.

Conclusion

Syncope, while often benign, can be a sign of serious underlying health issues such as cardiac disease, abnormal heart rhythms, or neurological disorders. Proper diagnosis and treatment are essential to managing syncope and preventing complications. By addressing the risk factors and causes, individuals can reduce the frequency of fainting episodes and maintain a better quality of life.

Your heart deserves the best care!


Don’t wait until it’s too late. Avicenna Cardiology provides expert, compassionate care for all your cardiovascular needs, from diagnosis to treatment. Whether you’re concerned about heart disease, or blood pressure issues, or seeking a second opinion, our specialists are here to help. Schedule your consultation today and start your journey to better heart health. Visit Avicenna Cardiology for more information and to book your appointment. Your heart deserves the best care!

Syncope FAQ

Diagnosing syncope involves a comprehensive evaluation that includes reviewing the patient's medical history, performing a physical examination, and conducting diagnostic tests. These tests may include an electrocardiogram (ECG) to monitor heart activity, blood tests, a tilt table test to assess how the body responds to changes in position and imaging studies like echocardiograms or MRIs. The goal is to identify the underlying cause of syncope.

Yes, syncope can sometimes be a sign of a serious medical condition, particularly if it is related to heart issues such as abnormal heart rhythms (cardiac syncope) or structural heart disease. Abnormal heart rhythm can lead to inefficient blood circulation and potential fainting episodes due to various types of arrhythmias, highlighting its significance in serious cardiovascular conditions. If fainting occurs frequently, without warning, or during physical activity, it may indicate a higher risk of sudden cardiac death or other cardiovascular problems. It’s important to seek medical attention if syncope occurs repeatedly or alongside symptoms like chest pain or shortness of breath.

Preventing syncope involves addressing the underlying cause and taking steps to avoid triggers. Some prevention strategies include staying hydrated, avoiding prolonged standing, wearing compression stockings to improve circulation, and recognizing early warning signs such as dizziness or lightheadedness. For those with cardiac or neurological causes of syncope, following a prescribed treatment plan is essential for managing the condition.

If someone faints due to syncope, it's important to ensure their safety by laying them flat on their back and elevating their legs to restore blood flow to the brain. Make sure they are breathing and keep their airway clear. If they do not regain consciousness quickly or if they experience chest pain, difficulty breathing, or other concerning symptoms, seek emergency medical assistance immediately.

About The Author

Azadeh Beheshtian, MD

Azadeh Beheshtian, MD

Dr. Azadeh Beheshtian is certified by the American Board of Internal Medicine in both cardiovascular disease and internal medicine. Her expertise lies in interventional cardiology and peripheral artery disease, with a special emphasis on women’s heart health. Along with her surgical skills, she prioritizes collaborating with patients to prevent serious cardiac or vascular incidents. Her method involves creating carefully tailored care plans aimed at optimizing patient health outcomes.